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Evolution, not Hadoop, is the Biggest Missing Block in Bioinformatics
A Biostar discussion started with – Uri Laserson from Cloudera: “Computational Biologist are reinventing the wheel for big data biology analysis, e.g. Cram = column storage, Galaxy = workflow sheduler,...
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Dan Graur elected as AAAS Fellow, Birney/Gerstein Quietly Drop Out of ENCODE
Strange things are happening lately !! Dan Graur, who was called troll by renowned social media scientists BioMickWatson and Daniel MacArthur, has been elected AAAS fellow, whereas ENCODE leaders Ewan...
View ArticleHappy New Year and a New Direction
Happy new year everyone ! Over the last three years, our blog focused on algorithms to analyze next-generation sequencing data. Most of the kinks on that front have been ironed out, whereas with...
View ArticlePoor People Need to Provide Bank Statements to Publish in PLoS
Adam Eyre-Walker is an accomplished evolutionary biologist, a breed of scientists out of favor in these days of NHGRI-dominated ENCODE big-data ‘science’. He did not receive any grant for about ten...
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Occasionality or Probability – What is the Right Term?
The concept of probability comes from mathematics and it has rigorous mathematical definition. It is a measure of distribution of outcomes of truly independent trials. Wikipedia describes it as – When...
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Bioinformaticians, Can You Pass That Exam?
Good knowledge of molecular evolution is essential to perform any research in bioinformatics and computational biology. Unlike the difficult 8th grade questions from early 19th century popping up over...
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Evolutionary Biologists to Follow – Sally Leys and Casey Dunn
If there is one area of evolutionary biology benefiting greatly from high-throughput sequencing, that is the study of ‘primitive’ or ‘lower’ animals. The animals like sponges were traditionally avoided...
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Eric H. Davidson (1937 – 2015)
I am incredibly sad to learn that Caltech professor and renowned developmental biologist Eric Davidson passed away last week. A few years back, he jokingly said to me at a sea urchin conference – “I am...
View ArticleMy Thoughts on Dying
Between 2000 and 2005, several ‘whole-genome’ papers were published on yeast and other model organisms, where the complete genome sequences were used to measure various cellular properties of the...
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